FGF10

Across TCGA patient cohorts, FGF10 mutation is significantly associated with the RNA expression of many other genes, with 2,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF10-associated genes across cancer lineages are PKP2, ABALON, and NDUFA5P7. Each is linked with FGF10 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF10-to-partner and partner-to-FGF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKP2 grouped by FGF10-low versus FGF10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF10→partner) and Y-score (partner→FGF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKP2 →	+0.987	+3.480	<.001	.002	3	3
UCEC	ABALON →	+0.589	+3.364	<.001	.004	3	2
STAD	NDUFA5P7 →	+0.099	+5.226	<.001	.003	3	2
SKCM	GPR119 →	+0.053	+2.992	<.001	.009	3	2
BLCA	RNU4-15P →	+0.558	+6.147	<.001	.002	3	2
UCEC	RNA5SP412 →	+0.751	+2.230	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,277 associations by consensus.

PKP2 by FGF10 expression — UCEC

Explore this box plot interactively →