FGF10

Across TCGA patient cohorts, FGF10 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF10-associated genes across cancer lineages are FoxM1, Annexin-1, and TFRC. Each is linked with FGF10 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF10-to-partner and partner-to-FGF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by FGF10-low versus FGF10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF10→partner) and Y-score (partner→FGF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.291	+2.700	.012	.006	3	2
UCEC	Annexin-1 →	+0.700	+3.019	.003	.019	3	2
UCEC	TFRC →	+0.906	+3.807	<.001	<.001	2	3
UCEC	CD31 →	-0.132	-2.311	.047	.034	3	2
UCEC	14-3-3_beta →	-0.110	-3.143	.014	.018	3	1
UCEC	FASN →	+0.614	+3.321	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

FoxM1 by FGF10 expression — UCEC

Explore this box plot interactively →