FGF10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FGF10 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FGF10-associated genes across cancer lineages are REG1B and RESP18. Each is linked with FGF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF10-to-partner and partner-to-FGF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1B grouped by FGF10-low versus FGF10-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF10→partner) and Y-score (partner→FGF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTREG1B →+1.039+5.169<.001.00531
BREASTRESP18 →+0.072+5.169<.001.00531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

REG1B by FGF10 expression — BREAST

Box plot of REG1B in FGF10-low vs FGF10-high samples in BREAST.

Explore this box plot interactively →

Exploration