FGD6

Across TCGA patient cohorts, FGD6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,238 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGD6-associated genes across cancer lineages are VEZT, ARSI, and RCOR3. Each is linked with FGD6 in more than 3 cancer types. Because this analysis shows association rather than direction, both FGD6-to-partner and partner-to-FGD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD6 versus VEZT in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD6→partner) and Y-score (partner→FGD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VEZT →	+0.520	+0.248	<.001	<.001	3	4
PDAC	ARSI →	+0.831	+0.280	<.001	<.001	3	4
OV	RCOR3 →	-0.792	-0.642	<.001	<.001	3	3
LSCC	DISP1 →	-0.412	-0.250	<.001	.002	3	3
OV	ARHGAP44 →	-0.830	-0.577	<.001	.002	3	3
LUAD	CDH3 →	+0.853	+0.233	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,238 associations by consensus.

FGD6 vs VEZT — BRCA

Explore this scatter interactively →