FGD4

Across TCGA patient cohorts, FGD4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,671 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGD4-associated genes across cancer lineages are VRK1, ZNF830, and KIF20A. Each is linked with FGD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both FGD4-to-partner and partner-to-FGD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD4 versus VRK1 in LSCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD4→partner) and Y-score (partner→FGD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	-0.629	-0.227	<.001	<.001	3	5
LSCC	ZNF830 →	-0.441	-0.214	<.001	<.001	3	4
OV	KIF20A →	-1.274	-0.796	.002	.004	3	4
OV	PLK1 →	-1.142	-0.905	.003	.002	3	4
GBM	ESCO2 →	-0.836	-0.261	<.001	<.001	3	4
OV	RRM2 →	-0.967	-0.798	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,671 associations by consensus.

FGD4 vs VRK1 — LSCC

Explore this scatter interactively →