FGD4

Across TCGA cell cohorts, FGD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,936 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FGD4-associated GO terms across cancer lineages are Phospholipid biosynthetic process, Glycerophospholipid metabolic process, and Vacuolar transport. Each is linked with FGD4 in more than 10 cancer types. Because this analysis shows association rather than direction, both FGD4-to-partner and partner-to-FGD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid biosynthetic process grouped by FGD4-low versus FGD4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD4→partner) and Y-score (partner→FGD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Phospholipid biosynthetic process →	+0.042	+1.649	.004	.001	3	10
OVARY	Glycerophospholipid metabolic process →	+0.035	+1.206	<.001	<.001	3	10
OVARY	Vacuolar transport →	+0.058	+1.061	<.001	<.001	2	11
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.280	+1.154	<.001	.004	3	10
CNS	Keratinocyte development →	-0.372	-0.703	.004	.003	3	9
OVARY	Endosome to lysosome transport →	+0.045	+0.834	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,936 associations by consensus.

Phospholipid biosynthetic process by FGD4 expression — LIVER

Explore this box plot interactively →