FGD3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,424 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGD3-associated proteins across cancer lineages are DEF6, DOCK8, and EVL. Each is linked with FGD3 in more than 8 cancer types. Because this analysis shows association rather than direction, both FGD3-to-partner and partner-to-FGD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD3 versus DEF6 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD3→partner) and Y-score (partner→FGD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMDEF6 →+0.611+0.842<.001<.00139
UCECDOCK8 →+0.613+0.781<.001<.00139
UCECEVL →+0.707+0.844<.001<.00139
OVFYB1 →+0.780+0.641.005.00339
GBMGPSM3 →+0.638+0.911<.001<.00139
OVIL16 →+0.775+0.919<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,424 associations by consensus.

FGD3 vs DEF6 — GBM

Per-sample scatter of FGD3 vs DEF6 in GBM (Pearson r = 0.70).

Explore this scatter interactively →

Exploration