FGD3

Across TCGA patient cohorts, FGD3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,503 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGD3-associated genes across cancer lineages are LILRA1, DOCK8, and RHOH. Each is linked with FGD3 in more than 8 cancer types. Because this analysis shows association rather than direction, both FGD3-to-partner and partner-to-FGD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD3 versus LILRA1 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD3→partner) and Y-score (partner→FGD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LILRA1 →	+0.646	+0.461	<.001	<.001	3	9
OV	DOCK8 →	+1.091	+0.494	<.001	<.001	3	9
BRCA	RHOH →	+1.155	+0.696	<.001	<.001	3	9
CCRCC	GAPT →	+1.053	+0.427	<.001	<.001	3	9
OV	CSF2RB →	+1.112	+0.433	<.001	<.001	3	8
HNSC	SLA2 →	+0.844	+0.310	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,503 associations by consensus.

FGD3 vs LILRA1 — OV

Explore this scatter interactively →