FGD2

Across TCGA patient cohorts, FGD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,042 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGD2-associated proteins across cancer lineages are RCSD1, SASH3, and SPN. Each is linked with FGD2 in more than 9 cancer types. Because this analysis shows association rather than direction, both FGD2-to-partner and partner-to-FGD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD2 versus RCSD1 in HNSC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD2→partner) and Y-score (partner→FGD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCSD1 →	+0.699	+1.104	<.001	<.001	3	10
HNSC	SASH3 →	+0.569	+1.031	<.001	<.001	3	10
OV	SPN →	+0.838	+0.875	<.001	<.001	3	10
OV	SPN_S355 →	+1.120	+0.671	<.001	<.001	3	10
UCEC	WAS →	+0.619	+0.788	<.001	<.001	3	10
UCEC	ADA2 →	+0.648	+0.857	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,042 associations by consensus.

FGD2 vs RCSD1 — HNSC

Explore this scatter interactively →