FGD1

Across TCGA patient cohorts, FGD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,011 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FGD1-associated proteins across cancer lineages are HUWE1, FGD1_T711, and NOSTRIN. Each is linked with FGD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FGD1-to-partner and partner-to-FGD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD1 versus HUWE1 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD1→partner) and Y-score (partner→FGD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HUWE1 →	+0.265	+0.682	<.001	.001	3	6
UCEC	FGD1_T711 →	+0.726	+0.762	<.001	<.001	3	6
BRCA	NOSTRIN →	-0.902	-0.692	<.001	.001	3	5
LSCC	SDC4 →	-0.551	-0.691	<.001	<.001	3	5
LUAD	FGD1_S135 →	+0.860	+0.818	<.001	<.001	3	5
LSCC	NAV1 →	+0.386	+0.518	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,011 associations by consensus.

FGD1 vs HUWE1 — GBM

Explore this scatter interactively →