FGD1

Across TCGA patient cohorts, FGD1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,332 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGD1-associated genes across cancer lineages are GMPS, TMEM17, and LENG9. Each is linked with FGD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGD1-to-partner and partner-to-FGD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGD1 versus GMPS in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD1→partner) and Y-score (partner→FGD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPS →	+0.814	+0.349	.001	<.001	3	3
LSCC	TMEM17 →	+1.081	+0.452	<.001	<.001	3	3
LUAD	LENG9 →	-0.880	-1.106	<.001	.002	3	3
LSCC	OLFML3 →	-0.904	-0.305	.002	.004	3	3
LSCC	TMEM156 →	-1.131	-0.308	<.001	.001	3	3
LSCC	HROB →	+0.659	+0.273	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,332 associations by consensus.

FGD1 vs GMPS — LSCC

Explore this scatter interactively →