FGD1

Across TCGA cell cohorts, FGD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,039 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGD1-associated GO terms across cancer lineages are Growth hormone secretion, Positive regulation of sodium ion transport, and Negative regulation of gene expression, epigenetic. Each is linked with FGD1 in more than 15 cancer types. Because this analysis shows association rather than direction, both FGD1-to-partner and partner-to-FGD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by FGD1-low versus FGD1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGD1→partner) and Y-score (partner→FGD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Growth hormone secretion →	+0.108	+1.440	.005	.001	3	16
PANCREAS	Positive regulation of sodium ion transport →	-0.227	-1.402	.001	<.001	3	13
STOMACH	Negative regulation of gene expression, epigenetic →	+0.063	+1.730	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Cell division →	+0.079	+1.209	.003	.008	3	13
BONE	Nucleosome organization →	+0.093	+0.852	.001	.002	3	13
BREAST	Renal vesicle formation →	+1.335	+1.289	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,039 associations by consensus.

Growth hormone secretion by FGD1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →