FGB

Across TCGA patient cohorts, FGB RNA expression is significantly associated with the go_rna of many other GO terms, with 6,658 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible FGB-associated GO terms across cancer lineages are Regulation of very-low-density lipoprotein particle remodeling, Glutamine family amino acid biosynthetic process, and Pyrimidine ribonucleoside triphosphate metabolic process. Each is linked with FGB in more than 11 cancer types. Because this analysis shows association rather than direction, both FGB-to-partner and partner-to-FGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of very-low-density lipoprotein particle remodeling grouped by FGB-low versus FGB-high in READ.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGB→partner) and Y-score (partner→FGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	Regulation of very-low-density lipoprotein particle remodeling →	+0.645	+1.170	<.001	<.001	2	12
ESCA	Glutamine family amino acid biosynthetic process →	+0.062	+1.522	<.001	<.001	3	8
TGCT	Pyrimidine ribonucleoside triphosphate metabolic process →	+0.049	+2.668	<.001	<.001	3	8
TGCT	Cellular glucuronidation →	-0.084	-1.546	<.001	<.001	3	8
TGCT	COPII-coated vesicle cargo loading →	+0.061	+1.714	<.001	<.001	3	8
CHOL	Acute inflammatory response →	+0.051	+3.289	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,658 associations by consensus.

Regulation of very-low-density lipoprotein particle remodeling by FGB expression — READ

Explore this box plot interactively →