FGB

Across TCGA patient cohorts, FGB protein abundance is significantly associated with the RNA expression of many other genes, with 14,352 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FGB-associated genes across cancer lineages are IL6, SLC2A3, and FLT1. Each is linked with FGB in more than 9 cancer types. Because this analysis shows association rather than direction, both FGB-to-partner and partner-to-FGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGB versus IL6 in CCRCC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGB→partner) and Y-score (partner→FGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IL6 →	+1.522	+0.517	<.001	.004	3	10
OV	SLC2A3 →	+1.340	+1.121	<.001	<.001	3	9
OV	FLT1 →	+1.246	+1.162	<.001	<.001	3	8
COAD	TREM1 →	+1.336	+1.249	<.001	<.001	3	8
OV	ADAMTS4 →	+1.057	+1.199	<.001	<.001	3	8
COAD	FCAR →	+0.872	+0.986	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,352 associations by consensus.

FGB vs IL6 — CCRCC

Explore this scatter interactively →