Across TCGA patient cohorts, FFAR4 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FFAR4-associated genes across cancer lineages are STAT3_pY705, Bak, and 4E-BP1. Each is linked with FFAR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FFAR4-to-partner and partner-to-FFAR4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR4→partner) and Y-score (partner→FFAR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.427	-3.459	.001	.005	3	1
UCEC	Bak →	+0.269	+2.321	.032	.035	3	1
UCEC	4E-BP1 →	+0.345	+2.837	.011	.035	2	2
UCEC	ACC1 →	+0.394	+2.321	.031	.035	2	1
UCEC	p38-MAPK →	-0.260	-3.459	.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

FFAR4 survival (RNA) · tumor vs normal (RNA) · all FFAR4 data types