FFAR3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FFAR3 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FFAR3 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher FFAR3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FFAR3 expression acts as an unfavorable survival marker.

BLCA, UCS, and THYM are the cancer types where FFAR3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSMedianAll0.0690.710<.00136view →
UCSOSMedianAll0.0070.689<.00124view →
THYMDFSMedianAll0.1230.871<.00112view →
READOSMedianII,III,IV0.1870.644.02312view →
LUADDFSMedianAll0.5230.793.0098view →
GBMDFSMedianAll0.0480.257.0016view →
SARCDFSMedianAll0.1210.591.0423view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration