Across TCGA patient cohorts, FFAR3 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FFAR3-associated genes across cancer lineages are Fibronectin, MEK1, and Notch1. Each is linked with FFAR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FFAR3-to-partner and partner-to-FFAR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR3→partner) and Y-score (partner→FFAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Fibronectin →	+0.467	+2.820	.006	.035	3	1
UCEC	MEK1 →	+0.442	+3.321	.021	.010	3	1
UCEC	Notch1 →	+0.215	+3.009	.003	.019	3	1
UCEC	p21 →	+0.285	+3.321	.004	.010	3	1
UCEC	PAI-1 →	+0.582	+3.169	.001	.019	3	1
UCEC	PDCD4 →	-0.584	-2.990	.017	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

FFAR3 survival (RNA) · tumor vs normal (RNA) · all FFAR3 data types