FFAR2

Across TCGA patient cohorts, FFAR2 mutation is significantly associated with the RNA expression of many other genes, with 761 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FFAR2-associated genes across cancer lineages are HMGN1P20, RN7SKP132, and RNU6-522P. Each is linked with FFAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FFAR2-to-partner and partner-to-FFAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGN1P20 grouped by FFAR2-low versus FFAR2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR2→partner) and Y-score (partner→FFAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HMGN1P20 →	+0.204	+3.423	<.001	.006	3	2
LUAD	RN7SKP132 →	+0.144	+5.108	<.001	.002	3	2
READ	RNU6-522P →	+1.222	+6.681	<.001	<.001	3	2
UCEC	H2AC14 →	+0.619	+3.923	.001	<.001	3	2
UCEC	UCN →	+0.513	+1.936	.009	.003	3	2
UCEC	NUDT2 →	+0.610	+4.032	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 761 associations by consensus.

HMGN1P20 by FFAR2 expression — LUAD

Explore this box plot interactively →