FFAR2

Across TCGA cell cohorts, FFAR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,325 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FFAR2-associated GO terms across cancer lineages are Positive regulation of endoplasmic reticulum unfolded protein response, Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, and Basement membrane disassembly. Each is linked with FFAR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FFAR2-to-partner and partner-to-FFAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of endoplasmic reticulum unfolded protein response grouped by FFAR2-low versus FFAR2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR2→partner) and Y-score (partner→FFAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.088	+0.728	<.001	<.001	3	6
PANCREAS	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress →	+0.086	+0.231	<.001	.008	3	6
BLOOD_Leukemia	Basement membrane disassembly →	+0.593	+0.721	.001	<.001	3	5
BREAST	Mitotic metaphase chromosome alignment →	-0.080	-0.730	<.001	<.001	3	4
BREAST	Regulation of mitotic nuclear division →	-0.066	-0.706	.003	.001	3	4
BREAST	Body fluid secretion →	+0.149	+0.825	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,325 associations by consensus.

Positive regulation of endoplasmic reticulum unfolded protein response by FFAR2 expression — BREAST

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