FFAR2

Across TCGA cell cohorts, FFAR2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FFAR2-associated genes across cancer lineages are ACER1, OR10W1, and SH3GL2. Each is linked with FFAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FFAR2-to-partner and partner-to-FFAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by FFAR2-low versus FFAR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR2→partner) and Y-score (partner→FFAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.079	+4.145	.003	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.821	+3.252	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACER1 by FFAR2 expression — LARGE_INTESTINE

Explore this box plot interactively →