FFAR1

Across TCGA patient cohorts, FFAR1 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FFAR1-associated genes across cancer lineages are CD8+ Tcm, CD4+ Tem, and CD4+ Tcm. Each is linked with FFAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FFAR1-to-partner and partner-to-FFAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by FFAR1-low versus FFAR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR1→partner) and Y-score (partner→FFAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.025	+2.198	.007	.039	3	2
HNSC	CD4+ Tem →	+0.032	+6.623	<.001	.019	3	1
HNSC	CD4+ Tcm →	+0.016	+5.468	<.001	.043	3	1
UCEC	CD8+ T-cells →	+0.017	+2.108	.004	.046	3	1
UCEC	CD8+ Tem →	+0.003	+4.481	<.001	.047	3	1
UCEC	Macrophages →	+0.021	+1.710	.002	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CD8+ Tcm by FFAR1 expression — UCEC

Explore this box plot interactively →