FFAR1

Across TCGA cell cohorts, FFAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,452 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FFAR1-associated GO terms across cancer lineages are Positive regulation of ruffle assembly, Regulation of keratinocyte apoptotic process, and Negative regulation of macroautophagy. Each is linked with FFAR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FFAR1-to-partner and partner-to-FFAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of ruffle assembly grouped by FFAR1-low versus FFAR1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR1→partner) and Y-score (partner→FFAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of ruffle assembly →	+0.194	+0.035	.005	.008	2	7
BLOOD_Lymphoma	Regulation of keratinocyte apoptotic process →	+0.092	+0.729	.004	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of macroautophagy →	+0.074	+0.141	<.001	.004	3	5
LUNG_NSCLC_LUAD	Regulation of ruffle assembly →	+0.154	+0.041	<.001	.003	2	6
LARGE_INTESTINE	Regulation of intrinsic apoptotic signaling pathway →	+0.044	+0.042	.001	.003	3	5
BLOOD_Leukemia	Positive regulation of intracellular mRNA localization →	+0.128	+0.485	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,452 associations by consensus.

Positive regulation of ruffle assembly by FFAR1 expression — OESOPHAGUS

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