FFAR1

Across TCGA cell cohorts, FFAR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FFAR1-associated genes across cancer lineages are LCN1, RIT2, and PABPC1L2A. Each is linked with FFAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FFAR1-to-partner and partner-to-FFAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCN1 grouped by FFAR1-low versus FFAR1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FFAR1→partner) and Y-score (partner→FFAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LCN1 →	+0.042	+4.544	.005	.003	3	1
SKIN	RIT2 →	+0.040	+6.022	<.001	.001	3	1
SKIN	PABPC1L2A →	+0.047	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LCN1 by FFAR1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →