FEZF2

Across TCGA patient cohorts, FEZF2 mutation is significantly associated with the RNA expression of many other genes, with 3,016 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FEZF2-associated genes across cancer lineages are SRP54, CEP76, and PSMD10. Each is linked with FEZF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FEZF2-to-partner and partner-to-FEZF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRP54 grouped by FEZF2-low versus FEZF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZF2→partner) and Y-score (partner→FEZF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRP54 →	+0.624	+2.917	<.001	<.001	3	2
UCEC	CEP76 →	+0.353	+2.010	.007	.001	3	2
UCEC	PSMD10 →	+0.420	+2.032	.004	.001	3	2
UCEC	PFN1 →	+0.318	+2.392	.008	<.001	3	2
UCEC	LRRC59 →	+0.720	+2.885	<.001	<.001	3	2
UCEC	EIF2B2 →	+0.433	+2.032	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,016 associations by consensus.

SRP54 by FEZF2 expression — UCEC

Explore this box plot interactively →