FEZF1

Across TCGA patient cohorts, FEZF1 mutation is significantly associated with the RNA expression of many other genes, with 4,136 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FEZF1-associated genes across cancer lineages are BRAT1, SEC24D, and RNU6-1082P. Each is linked with FEZF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FEZF1-to-partner and partner-to-FEZF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRAT1 grouped by FEZF1-low versus FEZF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZF1→partner) and Y-score (partner→FEZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BRAT1 →	+0.365	+2.456	.003	<.001	3	3
UCEC	SEC24D →	+0.635	+1.673	.001	.007	3	3
CESC	RNU6-1082P →	+0.346	+6.144	<.001	.001	3	2
COAD	GAPDHP17 →	+0.164	+6.721	<.001	<.001	3	2
COAD	RN7SL98P →	+0.311	+5.693	<.001	.003	3	2
UCEC	RANBP9 →	+0.404	+3.863	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,136 associations by consensus.

BRAT1 by FEZF1 expression — UCEC

Explore this box plot interactively →