FEZF1-AS1

Across TCGA pan-cancer cohorts, FEZF1-AS1 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated FEZF1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher FEZF1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FEZF1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and UVM show a favorable association.

MESO, KIRC, and ACC are the cancer types where FEZF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.289	0.474	.006	80	view →
KIRC	OS	Median	All	0.537	0.697	<.001	69	view →
ACC	DFS	Tertile	All	0.211	0.683	<.001	69	view →
LUSC	OS	Tertile	All	0.831	0.701	<.001	57	view →
CESC	DFS	Quartile	III,IV	0.536	0.894	.014	44	view →
LGG	DFS	Median	All	0.661	0.810	<.001	44	view →
KIRP	DFS	Median	All	0.839	0.948	<.001	43	view →
UVM	OS	Tertile	II,III,IV	0.955	0.632	.006	33	view →
ESCA	OS	Median	IV	0.222	0.698	.006	27	view →
UCEC	OS	Quartile	III,IV	0.909	0.756	.024	22	view →
LUAD	OS	Tertile	II,III,IV	0.710	0.469	.005	19	view →
HNSC	OS	Median	All	0.297	0.470	.003	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

FEZF1-AS1–MESO (OS)

Open the MESO breakdown →