FEZ2

Across TCGA patient cohorts, FEZ2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,708 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FEZ2-associated genes across cancer lineages are HEATR5A, SPTSSA, and NKD1. Each is linked with FEZ2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FEZ2-to-partner and partner-to-FEZ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FEZ2 versus HEATR5A in LUAD, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZ2→partner) and Y-score (partner→FEZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HEATR5A →	+0.417	+0.210	<.001	<.001	3	5
LSCC	SPTSSA →	+0.594	+0.186	<.001	<.001	3	4
UCEC	NKD1 →	-1.631	-0.188	<.001	<.001	3	3
BRCA	SEC23A →	+0.502	+0.182	<.001	<.001	3	3
LSCC	FAM177A1 →	+0.487	+0.195	<.001	.003	3	3
CCRCC	COMMD4P1 →	-0.518	-0.168	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,708 associations by consensus.

FEZ2 vs HEATR5A — LUAD

Explore this scatter interactively →