FEZ2

Across TCGA cell cohorts, FEZ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,059 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FEZ2-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Regulation of hippo signaling, and Regulation of stress-activated protein kinase signaling cascade. Each is linked with FEZ2 in more than 15 cancer types. Because this analysis shows association rather than direction, both FEZ2-to-partner and partner-to-FEZ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by FEZ2-low versus FEZ2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZ2→partner) and Y-score (partner→FEZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.277	+1.189	<.001	<.001	3	16
BONE	Regulation of hippo signaling →	+0.097	+0.950	<.001	.002	3	15
OESOPHAGUS	Regulation of stress-activated protein kinase signaling cascade →	+0.090	+1.123	.007	<.001	2	15
BONE	Positive regulation of cell-substrate junction organization →	+0.197	+0.836	<.001	<.001	3	13
BONE	Cellular response to abiotic stimulus →	+0.055	+1.233	.001	<.001	3	13
BONE	Cellular response to environmental stimulus →	+0.055	+1.233	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,059 associations by consensus.

Positive regulation of focal adhesion assembly by FEZ2 expression — BONE

Explore this box plot interactively →