FEZ1

Across TCGA patient cohorts, FEZ1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,294 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FEZ1-associated genes across cancer lineages are CNRIP1, ARHGEF6, and ZCCHC24. Each is linked with FEZ1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FEZ1-to-partner and partner-to-FEZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FEZ1 versus CNRIP1 in LSCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZ1→partner) and Y-score (partner→FEZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CNRIP1 →	+0.503	+0.501	<.001	<.001	3	3
GBM	ARHGEF6 →	+0.554	+0.549	<.001	<.001	3	3
LSCC	ZCCHC24 →	+0.722	+0.532	<.001	<.001	3	3
GBM	NXPH3 →	+0.928	+0.486	<.001	<.001	3	3
LUAD	LGALS2 →	+0.525	+0.259	.002	.002	3	2
GBM	RASSF2 →	+0.977	+0.481	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,294 associations by consensus.

FEZ1 vs CNRIP1 — LSCC

Explore this scatter interactively →