FEZ1

Across TCGA cell cohorts, FEZ1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FEZ1-associated genes across cancer lineages are SCGB3A2, OR51T1, and GSG1L2. Each is linked with FEZ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FEZ1-to-partner and partner-to-FEZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB3A2 grouped by FEZ1-low versus FEZ1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEZ1→partner) and Y-score (partner→FEZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SCGB3A2 →	+0.117	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
BLOOD_Leukemia	OR4A47 →	+0.022	+5.539	<.001	.003	3	1
CNS	F9 →	+0.042	+5.321	<.001	.005	3	1
CNS	LEUTX →	+0.226	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

SCGB3A2 by FEZ1 expression — BLOOD_Leukemia

Explore this box plot interactively →