FEV

Across TCGA pan-cancer cohorts, FEV RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FEV data layer compared with 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FEV RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FEV expression acts as an unfavorable survival marker, although some lineages such as PAAD and KICH show a favorable association.

LUAD, UCEC, and LUSC are the cancer types where FEV RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.191	0.462	.003	59	view →
UCEC	OS	Median	IV	0.491	0.839	.006	54	view →
LUSC	DFS	Median	III,IV	0.328	0.609	.006	50	view →
PAAD	DFS	Tertile	All	0.348	0.164	.002	47	view →
KIRP	DFS	Median	IV	0.032	0.473	.003	32	view →
THCA	OS	Quartile	III,IV	0.876	0.997	.001	30	view →
LIHC	OS	Quartile	III,IV	0.157	0.425	.014	22	view →
MESO	DFS	Quartile	III,IV	0.164	0.801	.010	18	view →
KICH	OS	Median	All	1.000	0.928	.018	17	view →
ESCA	DFS	Quartile	III,IV	0.239	0.540	.008	12	view →
UCS	DFS	Tertile	II,III,IV	0.556	0.149	.030	12	view →
COAD	DFS	Tertile	III,IV	0.496	0.768	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FEV–LUAD (DFS)

Open the LUAD breakdown →