FETUB

Across TCGA patient cohorts, FETUB mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FETUB-associated genes across cancer lineages are eIF4E, PCNA, and FoxM1. Each is linked with FETUB in more than 1 cancer types. Because this analysis shows association rather than direction, both FETUB-to-partner and partner-to-FETUB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by FETUB-low versus FETUB-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FETUB→partner) and Y-score (partner→FETUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eIF4E →	+0.218	+2.832	.026	.035	3	2
COAD	PCNA →	+0.288	+2.815	.034	.036	3	2
UCEC	FoxM1 →	+0.238	+2.222	.030	.011	3	1
UCEC	JNK_pT183_Y185 →	-0.188	-3.459	.008	.005	3	1
UCEC	Notch1 →	+0.201	+2.331	<.001	.019	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.395	-2.321	.038	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

eIF4E by FETUB expression — COAD

Explore this box plot interactively →