FETUB

Across TCGA cell cohorts, FETUB mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FETUB-associated genes across cancer lineages are HRG, SPATA19, and WFDC12. Each is linked with FETUB in more than 1 cancer types. Because this analysis shows association rather than direction, both FETUB-to-partner and partner-to-FETUB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HRG grouped by FETUB-low versus FETUB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FETUB→partner) and Y-score (partner→FETUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HRG →	+0.347	+3.855	<.001	.007	3	1
BLOOD_Leukemia	SPATA19 →	+0.018	+4.984	<.001	.002	3	1
BLOOD_Leukemia	WFDC12 →	+0.194	+3.874	<.001	.005	3	1
BLOOD_Leukemia	FAM71E2 →	+0.009	+4.060	<.001	.003	3	1
BLOOD_Leukemia	TRIM49B →	+0.126	+3.874	<.001	.005	3	1
BLOOD_Leukemia	ZPBP2 →	+0.610	+3.777	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

HRG by FETUB expression — BLOOD_Leukemia

Explore this box plot interactively →