FERMT3

Across TCGA patient cohorts, FERMT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FERMT3-associated proteins across cancer lineages are PTPN6, PTPN7, and RASAL3. Each is linked with FERMT3 in more than 9 cancer types. Because this analysis shows association rather than direction, both FERMT3-to-partner and partner-to-FERMT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FERMT3 versus PTPN6 in GBM, with a Pearson correlation of 0.90.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FERMT3→partner) and Y-score (partner→FERMT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPN6 →	+0.840	+1.100	<.001	<.001	3	10
COAD	PTPN7 →	+0.591	+0.899	<.001	<.001	3	10
GBM	RASAL3 →	+0.496	+1.069	<.001	<.001	3	10
GBM	ARHGAP45 →	+0.747	+1.050	<.001	<.001	3	10
GBM	WAS →	+0.820	+1.158	<.001	<.001	3	10
GBM	CORO1A →	+0.680	+1.072	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,712 associations by consensus.

FERMT3 vs PTPN6 — GBM

Explore this scatter interactively →