FERMT3

Across TCGA cell cohorts, FERMT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,021 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FERMT3-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Golgi disassembly, and Regulation of protein localization to mitochondrion. Each is linked with FERMT3 in more than 6 cancer types. Because this analysis shows association rather than direction, both FERMT3-to-partner and partner-to-FERMT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by FERMT3-low versus FERMT3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FERMT3→partner) and Y-score (partner→FERMT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of chromosome organization →	+0.053	+0.695	.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Golgi disassembly →	+0.073	+0.411	.006	.006	3	6
SOFT_TISSUE	Regulation of protein localization to mitochondrion →	+0.096	+1.750	<.001	<.001	3	6
LUNG_SCLC	Positive regulation of protein localization to mitochondrion →	+0.071	+0.944	.002	<.001	3	6
BONE	Positive regulation of gene expression, epigenetic →	+0.066	+1.900	.002	<.001	3	6
BONE	Negative regulation of RNA splicing →	+0.089	+2.154	.006	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,021 associations by consensus.

Positive regulation of chromosome organization by FERMT3 expression — URINARY_TRACT

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