FERMT2

Across TCGA patient cohorts, FERMT2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,222 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FERMT2-associated genes across cancer lineages are TIMP3, SYDE1, and SGCA. Each is linked with FERMT2 in more than 9 cancer types. Because this analysis shows association rather than direction, both FERMT2-to-partner and partner-to-FERMT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FERMT2 versus TIMP3 in OV, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FERMT2→partner) and Y-score (partner→FERMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TIMP3 →	+2.232	+0.622	<.001	<.001	3	10
BRCA	SYDE1 →	+0.898	+0.653	<.001	<.001	3	10
LUAD	SGCA →	+0.991	+0.316	<.001	<.001	3	10
OV	PMP22 →	+1.129	+0.547	<.001	<.001	3	10
OV	CALD1 →	+1.503	+0.562	<.001	<.001	3	10
BRCA	RHOJ →	+1.132	+0.734	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,222 associations by consensus.

FERMT2 vs TIMP3 — OV

Explore this scatter interactively →