FERMT1

Across TCGA patient cohorts, FERMT1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,042 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FERMT1-associated genes across cancer lineages are SDCBP2, CSNK2A1, and PI3. Each is linked with FERMT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FERMT1-to-partner and partner-to-FERMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FERMT1 versus SDCBP2 in LUAD, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FERMT1→partner) and Y-score (partner→FERMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SDCBP2 →	+1.380	+0.636	<.001	<.001	3	5
COAD	CSNK2A1 →	+0.594	+0.436	<.001	<.001	3	4
LSCC	PI3 →	+2.292	+0.573	<.001	<.001	3	4
COAD	MKKS →	+0.684	+0.479	<.001	<.001	3	4
COAD	ITPA →	+0.645	+0.429	<.001	.001	3	4
COAD	SLFN11 →	-0.784	-0.464	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,042 associations by consensus.

FERMT1 vs SDCBP2 — LUAD

Explore this scatter interactively →