FERMT1

Across TCGA cell cohorts, FERMT1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FERMT1-associated genes across cancer lineages are OR10Q1, GPR26, and SCGB3A2. Each is linked with FERMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FERMT1-to-partner and partner-to-FERMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10Q1 grouped by FERMT1-low versus FERMT1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FERMT1→partner) and Y-score (partner→FERMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10Q1 →	+0.653	+5.643	<.001	.002	3	2
BLOOD_Leukemia	GPR26 →	+0.077	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.144	+4.922	<.001	.009	3	1
BLOOD_Leukemia	LRRC55 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IQCM →	+0.038	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR10Q1 by FERMT1 expression — LUNG_SCLC

Explore this box plot interactively →