Across TCGA patient cohorts, FER1L6 mutation is significantly associated with the RNA expression of many other genes, with 8,035 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FER1L6-associated genes across cancer lineages are MND1, SKA1, and SPC24. Each is linked with FER1L6 in more than 5 cancer types. Because this analysis shows association rather than direction, both FER1L6-to-partner and partner-to-FER1L6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER1L6→partner) and Y-score (partner→FER1L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MND1 →	+0.657	+1.691	<.001	<.001	3	6
COAD	SKA1 →	+0.744	+3.807	<.001	<.001	3	5
UCEC	SPC24 →	+0.468	+1.285	.001	.001	3	5
UCEC	SNRPD1 →	+0.312	+1.560	.001	<.001	3	5
SKCM	CDK1 →	+0.581	+1.122	<.001	<.001	3	5
STAD	TYMS →	+0.764	+2.733	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,035 associations by consensus.

Exploration

FER1L6 survival (RNA) · tumor vs normal (RNA) · all FER1L6 data types