FER1L6-AS2

Across TCGA pan-cancer cohorts, FER1L6-AS2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FER1L6-AS2 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher FER1L6-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FER1L6-AS2 expression acts as an unfavorable survival marker, although some lineages such as READ and LGG show a favorable association.

LIHC, THYM, and DLBC are the cancer types where FER1L6-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.560	0.739	<.001	41	view →
THYM	OS	Tertile	All	0.860	1.000	.004	33	view →
DLBC	OS	Quartile	III,IV	0.610	1.000	.006	24	view →
READ	OS	Median	III,IV	0.916	0.297	.005	20	view →
LGG	DFS	Tertile	All	0.895	0.782	<.001	16	view →
LUAD	OS	Tertile	All	0.772	0.855	.021	15	view →
THCA	OS	Quartile	II,III,IV	0.541	0.824	.002	14	view →
CESC	DFS	Tertile	II,III,IV	0.261	0.575	.019	12	view →
PRAD	OS	Tertile	All	0.944	0.993	.002	12	view →
UVM	DFS	Tertile	III,IV	0.200	0.703	.044	9	view →
SKCM	DFS	Tertile	IV	0.654	0.186	.046	9	view →
MESO	OS	Tertile	All	0.252	0.558	.042	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FER1L6-AS2–LIHC (OS)

Open the LIHC breakdown →