FER

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FER protein abundance is significantly associated with the RNA expression of many other genes, with 13,035 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FER-associated genes across cancer lineages are ZCCHC24, TIMP3, and SRPX. Each is linked with FER in more than 7 cancer types. Because this analysis shows association rather than direction, both FER-to-partner and partner-to-FER results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FER versus ZCCHC24 in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER→partner) and Y-score (partner→FER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAZCCHC24 →+1.131+0.314<.001<.00138
UCECTIMP3 →+1.268+0.251<.001<.00137
BRCASRPX →+1.357+0.388<.001<.00137
CCRCCDCN →+1.732+0.158<.001.00237
BRCAPLSCR4 →+1.224+0.283<.001<.00137
BRCARECK →+0.859+0.263<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,035 associations by consensus.

FER vs ZCCHC24 — BRCA

Per-sample scatter of FER vs ZCCHC24 in BRCA (Pearson r = 0.62).

Explore this scatter interactively →

Exploration