FER

Across TCGA patient cohorts, FER mutation is significantly associated with the RNA expression of many other genes, with 3,915 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FER-associated genes across cancer lineages are SNORD90, AOC2, and SLF1. Each is linked with FER in more than 2 cancer types. Because this analysis shows association rather than direction, both FER-to-partner and partner-to-FER results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD90 grouped by FER-low versus FER-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER→partner) and Y-score (partner→FER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD90 →	+0.196	+1.670	.001	.006	3	3
UCEC	AOC2 →	+0.907	+2.745	<.001	<.001	3	3
UCEC	SLF1 →	+0.569	+2.432	<.001	<.001	3	3
UCEC	EME1 →	+0.736	+2.126	<.001	<.001	3	3
UCEC	KCNJ15 →	-0.664	-2.094	.004	<.001	3	3
UCEC	SENP3 →	+0.464	+2.279	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,915 associations by consensus.

SNORD90 by FER expression — UCEC

Explore this box plot interactively →