FER

Across TCGA cell cohorts, FER RNA expression is significantly associated with the go_rna of many other GO terms, with 4,605 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FER-associated GO terms across cancer lineages are Negative regulation of microtubule depolymerization, Positive regulation of organelle assembly, and Microtubule polymerization or depolymerization. Each is linked with FER in more than 12 cancer types. Because this analysis shows association rather than direction, both FER-to-partner and partner-to-FER results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of microtubule depolymerization grouped by FER-low versus FER-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FER→partner) and Y-score (partner→FER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of microtubule depolymerization →	+0.150	+0.959	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.075	+1.090	<.001	<.001	3	12
STOMACH	Microtubule polymerization or depolymerization →	+0.085	+1.184	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule polymerization →	+0.117	+1.187	<.001	<.001	3	12
BONE	Positive regulation of cytoskeleton organization →	+0.077	+0.791	.001	.002	3	12
BREAST	mRNA destabilization →	+0.058	+0.853	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,605 associations by consensus.

Negative regulation of microtubule depolymerization by FER expression — BONE

Explore this box plot interactively →