FER

Across TCGA cell cohorts, FER mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FER-associated genes across cancer lineages are TFDP3, VWC2, and ZNF723. Each is linked with FER in more than 1 cancer types. Because this analysis shows association rather than direction, both FER-to-partner and partner-to-FER results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFDP3 grouped by FER-low versus FER-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER→partner) and Y-score (partner→FER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TFDP3 →	+0.019	+4.857	<.001	<.001	3	1
OESOPHAGUS	VWC2 →	+0.080	+4.857	<.001	<.001	3	1
OESOPHAGUS	ZNF723 →	+0.017	+4.392	<.001	.003	3	1
LUNG_NSCLC_LUAD	GNG8 →	+0.268	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.015	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	MS4A13 →	+0.131	+5.228	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

TFDP3 by FER expression — OESOPHAGUS

Explore this box plot interactively →