FEN1

Across TCGA patient cohorts, FEN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,067 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FEN1-associated proteins across cancer lineages are RRM1, UNG_T60, and CDK1. Each is linked with FEN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FEN1-to-partner and partner-to-FEN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FEN1 versus RRM1 in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FEN1→partner) and Y-score (partner→FEN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM1 →	+0.541	+1.132	<.001	<.001	3	10
LSCC	UNG_T60 →	+0.947	+0.934	<.001	<.001	3	10
LUAD	CDK1 →	+0.883	+0.862	<.001	<.001	3	10
LUAD	ECT2_T359 →	+1.390	+0.923	<.001	<.001	3	10
LUAD	MCM2 →	+0.819	+0.847	<.001	<.001	3	10
OV	MCM2_S41 →	+0.755	+0.743	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,067 associations by consensus.

FEN1 vs RRM1 — UCEC

Explore this scatter interactively →