FEM1B

Across TCGA patient cohorts, FEM1B mutation is significantly associated with the RNA expression of many other genes, with 2,084 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FEM1B-associated genes across cancer lineages are MIR6085, RNY4P16, and SCGB1C1. Each is linked with FEM1B in more than 1 cancer types. Because this analysis shows association rather than direction, both FEM1B-to-partner and partner-to-FEM1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6085 grouped by FEM1B-low versus FEM1B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEM1B→partner) and Y-score (partner→FEM1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6085 →	+0.444	+3.659	<.001	.009	3	2
LUSC	RNY4P16 →	+0.377	+5.148	<.001	.002	3	2
STAD	SCGB1C1 →	+0.187	+4.005	<.001	.006	3	2
UCEC	MTATP6P21 →	+0.286	+2.060	<.001	.002	3	2
COAD	EZHIP →	+0.677	+3.387	<.001	.007	3	1
COAD	LCE1C →	+0.169	+4.246	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,084 associations by consensus.

MIR6085 by FEM1B expression — LUAD

Explore this box plot interactively →