FEM1B

Across TCGA cell cohorts, FEM1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,795 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FEM1B-associated GO terms across cancer lineages are Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway, Dosage compensation by inactivation of X chromosome, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with FEM1B in more than 16 cancer types. Because this analysis shows association rather than direction, both FEM1B-to-partner and partner-to-FEM1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway grouped by FEM1B-low versus FEM1B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FEM1B→partner) and Y-score (partner→FEM1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.168	+1.138	<.001	<.001	3	17
LARGE_INTESTINE	Dosage compensation by inactivation of X chromosome →	+0.089	+0.902	<.001	<.001	3	16
OESOPHAGUS	Regulation of ubiquitin-dependent protein catabolic process →	+0.065	+0.707	.004	.007	3	14
OESOPHAGUS	Negative regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.083	+0.811	.001	.001	2	15
LARGE_INTESTINE	Sex-chromosome dosage compensation →	+0.090	+0.911	<.001	<.001	3	14
STOMACH	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.094	+0.761	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,795 associations by consensus.

Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway by FEM1B expression — OESOPHAGUS

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