FEM1A

Across TCGA patient cohorts, FEM1A mutation is significantly associated with the RNA expression of many other genes, with 957 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FEM1A-associated genes across cancer lineages are RN7SL717P, ACD, and SUGT1P4. Each is linked with FEM1A in more than 1 cancer types. Because this analysis shows association rather than direction, both FEM1A-to-partner and partner-to-FEM1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL717P grouped by FEM1A-low versus FEM1A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEM1A→partner) and Y-score (partner→FEM1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL717P →	+0.058	+3.362	.001	.006	3	2
UCEC	ACD →	+0.439	+2.436	<.001	.001	3	2
LUSC	SUGT1P4 →	+0.192	+5.578	<.001	.002	3	2
COAD	REXO1L8P →	+0.015	+4.142	<.001	.006	3	2
UCEC	MEIG1 →	-0.481	-2.297	.004	.006	3	2
UCEC	RNU6-222P →	+0.526	+2.376	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 957 associations by consensus.

RN7SL717P by FEM1A expression — SKCM

Explore this box plot interactively →