Across TCGA pan-cancer cohorts, FECHP1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FECHP1’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where FECHP1 RNA is repressed in tumor relative to normal tissue. In most cancer types FECHP1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA are the cancer types where FECHP1 tumor–normal differential expression is most reproducible.