FECH

Across TCGA patient cohorts, FECH RNA expression is significantly associated with the protein abundance of many other proteins, with 13,601 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FECH-associated proteins across cancer lineages are SMAD4, RELCH, and TXNL1. Each is linked with FECH in more than 7 cancer types. Because this analysis shows association rather than direction, both FECH-to-partner and partner-to-FECH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FECH versus SMAD4 in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FECH→partner) and Y-score (partner→FECH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SMAD4 →	+0.291	+0.315	<.001	<.001	3	8
BRCA	RELCH →	+0.222	+0.406	<.001	<.001	3	6
LSCC	TXNL1 →	+0.365	+0.635	<.001	<.001	3	6
COAD	NARS1 →	+0.353	+0.726	<.001	<.001	3	6
BRCA	RPRD1A →	+0.419	+0.713	<.001	<.001	3	5
LSCC	SMAD2 →	+0.370	+0.683	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,601 associations by consensus.

FECH vs SMAD4 — PDAC

Explore this scatter interactively →